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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPG2 All Species: 6.36
Human Site: S398 Identified Species: 14
UniProt: P98160 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98160 NP_005520.4 4391 468798 S398 E S D C P D R S D E F G C M P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099299 4392 468662 S398 E S D C P D R S D E F G C M P
Dog Lupus familis XP_535371 2720 290354
Cat Felis silvestris
Mouse Mus musculus Q05793 3707 398275
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518520 1150 124768
Chicken Gallus gallus NP_001001876 4071 432826 C313 G C G T P S P C E P N E F K C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001120939 3407 371297
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027037 4179 461773 S357 F Y H C N D M S D E K S C E Q
Honey Bee Apis mellifera XP_393220 3382 373579
Nematode Worm Caenorhab. elegans Q06561 3375 369033
Sea Urchin Strong. purpuratus XP_001186142 2326 251883
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.8 51.7 N.A. 72.7 N.A. N.A. 20.8 58.1 N.A. 45.2 N.A. 22.1 25.7 24.2 24.2
Protein Similarity: 100 N.A. 98.6 54.6 N.A. 77.8 N.A. N.A. 23.2 69.8 N.A. 57.4 N.A. 35.9 39.4 37.9 34.7
P-Site Identity: 100 N.A. 100 0 N.A. 0 N.A. N.A. 0 6.6 N.A. 0 N.A. 40 0 0 0
P-Site Similarity: 100 N.A. 100 0 N.A. 0 N.A. N.A. 0 13.3 N.A. 0 N.A. 40 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 28 0 0 0 10 0 0 0 0 28 0 10 % C
% Asp: 0 0 19 0 0 28 0 0 28 0 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 0 0 10 28 0 10 0 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 19 0 10 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 0 0 0 19 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 19 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 28 0 10 0 0 10 0 0 0 0 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % R
% Ser: 0 19 0 0 0 10 0 28 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _